3D amino acid structure
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3D Amino Acids - Augmented Reality
Amino acids are organic compounds that contain amino[a] (−NH+3) and carboxylic acid (−CO2H) functional groups, along with a side chain (R group) specific to each amino acid. The elements present in every amino acid are carbon (C), hydrogen (H), oxygen (O), and nitrogen (N) (CHON). In addition sulfur (S) is present in the side chains of cysteine and methionine, and selenium (Se).
Abstract
The amino acid sequence of a protein is the key to understanding its structure and ultimately its function in the cell. This paper addresses the fundamental issue of encoding amino acids in ways that the representation of such a protein sequence facilitates the decoding of its information content. We show that a feature-based representation in a three-dimensional (3D) space derived from amino acid substitution matrices provides an adequate representation that can be used for direct comparison of protein sequences based on geometry. We measure the performance of such a representation in the context of the protein structural fold prediction problem. We compare the results of classifying different sets of proteins belonging to distinct structural folds against classifications of the same proteins obtained from sequence alone or directly from structural information. We find that sequence alone performs poorly as a structure classifier. We show in contrast that the use of the three dimensional representation of the sequences significantly improves the classification accuracy. We conclude with a discussion of the current limitations of such a representation and with a description of potential improvements.
About this app
Amino Acids is a neatly organized study app with detailed information, and quiz questions for the 20 major amino acids.
The app is intended to help students in biochemistry courses. It can also be used by others as a useful reference!
You can search the amino acids by name, code, codons, charge, and polarity! The quiz feature tests your knowledge of the structures, and provides feedback with simple stats.
Amino acids contain organic compounds like amile and carboxyl. They are responsible for giving cells their structure. There are 22 amino acids, out of the 22, 9 are essential and food containing all these essential 9 amino acids are know as complete proteins.
What's new
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